Gough and Millar called Kreuk to WB's studios in Burbank, California to audition for the role of Clark Kent's first love, Lana Lang. For a while, Kreuk was starring on both Smallville and Edgemont, although her role on Edgemont slightly diminished over time. After seven seasons, Kreuk left Smallville in the beginning of 2008, when her character leaves town.
She returned as a guest star in the show's 8th season for five episodes to conclude her storyline.
Kristin and her beau Mark met each other for the first time in 2004 and soon after, the couple started dating each other in September.
Back then the couple dated each other for few months and broke up.
A series, airing on The WB and later The CW (from 2001 to 2011), that chronicles Clark Kent's adolescence as he comes into his powers and eventually takes on the mantle of Superman.
The show started out as more of a Teen Drama, focusing largely on Clark's interactions with his friends, family, and Love Interests, and how this leads to his development as a Super Hero.
She played Hannah, a computer troubleshooter who joins the Buy More Nerd Herd after being laid off from her previous job.In mid-2004, Kreuk took the role of Tenar for the Sci Fi Channel two-part miniseries Legend of Earthsea.The miniseries was filmed in Vancouver, directed by Rob Lieberman and broadcast on December 13, 2004.In 2010, she portrayed Ben Hur's sister Tirzah in the TV movie Ben Hur, which aired in Canada and later on ABC in the United States.Kreuk was involved with two pilots that did not get picked up: an NBC 2010 sitcom entitled Hitched (which was co-created by Josh Schwartz, who was also the creator of Chuck) The series finale aired on August 25, 2016.